Verified open opportunity. NIH PAR-25-144 supports rigorous dissemination and implementation research focused on overcoming barriers to the adoption, adaptation, integration, sustainability, scale-up, spread, and appropriate de-implementation of evidence-based health interventions, practices, programs, tools, treatments, guidelines, and policies.
Opportunity snapshot
- Funding opportunity: Dissemination and Implementation Research in Health (R01 Clinical Trial Optional)
- Number: PAR-25-144
- Issuer: National Institutes of Health, with multiple participating Institutes and Centers.
- Next new-application deadline: October 5, 2026 at 5:00 PM local time of the applicant organization.
- Next renewal/resubmission/revision deadline: November 5, 2026 at 5:00 PM local time of the applicant organization.
- Funding: Application budgets are not capped but must reflect the actual needs of the proposed project.
- Project period: Up to five years.
- Cost sharing: Not required.
- Clinical trial: Optional.
What NIH is seeking
Responsive projects may identify, develop, or test strategies that improve implementation outcomes such as acceptability, feasibility, adoption, fidelity, penetration, sustainability, scale-up, and spread of evidence-based interventions in clinical, public-health, and community settings. The NOFO also supports dissemination research, de-implementation of ineffective or low-value practices, implementation methods and measures, economic evaluations, multilevel strategies, health-disparities implementation research, and rigorous stakeholder-engaged designs.
All applications must fall within the mission of at least one participating NIH Institute or Center. Institute-specific interests vary. For example, NHLBI identifies digital health interventions, data science and analytics, community-engaged research, and implementation work in low-resource settings among areas of interest; NEI expressly identifies telehealth and related digital-health strategies in vision-care implementation research.
Eligibility and submission
Eligible organization types include public and private institutions of higher education, nonprofits, small businesses and other for-profit organizations, state and local governments, tribal entities, independent school districts, faith- and community-based organizations, and other eligible entities listed in the NOFO. Cost sharing is not required. Applications may be submitted through NIH ASSIST, an institutional system-to-system solution, or Grants.gov Workspace, with eRA Commons used for tracking.
Arkansas relevance
Arkansas universities, health systems, research institutes, public-health organizations, and other eligible entities with evidence-based healthcare interventions and strong implementation-science, rural-health, telehealth, behavioral-health, chronic-disease, aging, maternal/pediatric, or community-health programs may be realistic applicants. Strong concepts should begin with an evidence-based intervention and a scientifically justified implementation question, rather than treating technology acquisition by itself as the research objective.
N9+ / Dr. Miltie fit
Conditional supporting fit. N9+ should not be represented as automatically allowable or as the evidence-based intervention itself. A legitimate role may exist where guided remote examination, structured physiologic or vital-sign capture, connected-health data, or remote-care workflow support is scientifically material to a qualifying evidence-based telehealth or remote-care implementation strategy. A partner-led or subcontract structure with a qualified Arkansas research institution is more credible than assuming a direct-prime role solely because for-profit entities are formally eligible.
Controlling source
NIH PAR-25-144 official funding opportunity announcement. Applicants should review the full NOFO, current NIH application guidance, and all linked amendments/notices before submission.