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PA-25-306

NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)

Official Grants.gov opportunity PA-25-306 from National Institutes of Health. Requires full eligibility, amount, controlling deadline, award-type and duplication QA before publication.

FundingApplicant-level ceiling not stated in the retrieved federal synopsis; verify in full NOFO.
Deadline2028-01-07 (official deadline clock time and time zone must be checked in NOFO)
Last verifiedAtlas review
Required next actionReview the official full announcement, amendments and submission portal requirements before applying.

Broad Eligibility

State governments; City or township governments; Special district governments; Small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; Others (see text field entitled "Additional Information on Eligibility" for clarification); Native American tribal organizations (other than Federally recognized tribal governments); For profit organizations other than small businesses; Native American tribal governments (Federally recognized); Public housing authorities/Indian housing authorities; Private institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; County governments; Public and State controlled institutions of higher education

Official funding announcement — preliminary draft

Funder: National Institutes of Health

Opportunity number: PA-25-306

Official listed status: posted

Closing information: 2028-01-07 (official deadline clock time and time zone must be checked in NOFO)

Award disclosure: Applicant-level ceiling not stated in the retrieved federal synopsis; verify in full NOFO.

Applicant categories in federal synopsis: State governments; City or township governments; Special district governments; Small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; Others (see text field entitled "Additional Information on Eligibility" for clarification); Native American tribal organizations (other than Federally recognized tribal governments); For profit organizations other than small businesses; Native American tribal governments (Federally recognized); Public housing authorities/Indian housing authorities; Private institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; County governments; Public and State controlled institutions of higher education

Federal synopsis

The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research. This Parent Notice of Funding Opportunity requires that at least 1 clinical trial be proposed. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.Applicants should note that some ICs (see Related Notices) only accept applications proposing mechanistic studies that meet NIH's definition of a clinical trial through this funding opportunity announcement.

Draft intake record. Eligibility, program terms, current amendments and applicant ceiling must be independently verified before publishing.

Official Grants.gov opportunity and NOFO

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Source verificationOfficial government source · www.grants.govAtlas last verified this record during its latest review. Always use the funder's current application materials, amendments and portal instructions as the controlling source.View source and application materials ↗