ActiveAtlas Opportunity Score 88/100
RFA-MH-27-180
NIH Advancing Research on Empirically-Supported Interventions for Older Adults Living with Serious Mental Illness (SMI) (R01 Clinical Trial Optional) – RFA-MH-27-180
NIMH RFA-MH-27-180 supports research to optimize, deliver, sustain, and evaluate empirically-supported interventions for adults age 50 and older living with serious mental illness. Applications are due October 15, 2026 at 5:00 PM local applicant time.
FundingNIMH intends to commit $3,000,000 in FY 2027 to fund up to 5 or 6 awards. Application budgets are not limited but must reflect the actual needs of the proposed project. Maximum project period: 5 years.
DeadlineOctober 15, 2026 at 5:00 PM local time of the applicant organization. Open date: September 15, 2026.
Last verifiedOctober 3, 2026
Required next actionConfirm scientific responsiveness to older-adult serious mental illness, a qualified PI and multidisciplinary research team, established clinical or community practice partners, appropriate preliminary evidence, human-subjects and clinical-trial requirements as applicable, NIMH data-sharing and common-data-element requirements, active registrations, and a submission plan through an authorized NIH channel before the October 15, 2026 deadline.
Broad Eligibility
Eligible organization types include public and private institutions of higher education, qualifying nonprofits, small businesses and other for-profit organizations, state and local governments, Tribal governments and organizations, independent school districts, public and Indian housing authorities, faith-based and community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions, subject to the full NIH eligibility rules. Cost sharing is not required.
Atlas Analysis
Atlas Opportunity Score 88/100. Strong behavioral-health and healthcare-research relevance for studies focused on adults age 50 and older living with serious mental illness. NIMH seeks practice-relevant intervention, services, implementation, and systems research conducted in real-world care or community settings. The R01 may include or omit a clinical trial. The 2026 application is due October 15, 2026 at 5:00 PM local time of the applicant organization. NIMH intends to commit $3,000,000 in FY 2027 for up to five or six awards; application budgets are not capped but must reflect actual project needs, and the maximum project period is five years.
The National Institutes of Health, National Institute of Mental Health, has opened Advancing Research on Empirically-Supported Interventions for Older Adults Living with Serious Mental Illness (SMI) (R01 Clinical Trial Optional), opportunity RFA-MH-27-180, Assistance Listing 93.242.
The opportunity supports research focused on improving the optimization, delivery, sustainability, and effectiveness of empirically-supported interventions for adults age 50 and older living with serious mental illness. Supported work may address evidence-based drugs, devices, psychotherapies, behavioral treatments, case-management services, implementation strategies, care transitions, and coordination across mental health, primary care, long-term care, healthcare, and social-service systems.
Deadline: October 15, 2026 at 5:00 PM local time of the applicant organization. The opportunity opened September 15, 2026. Only new applications are allowed.
Funding: NIMH intends to commit $3,000,000 in FY 2027 to fund up to five or six awards. Application budgets are not formally limited but must reflect the actual needs of the proposed project. The maximum project period is five years. Cost sharing is not required.
Eligibility: Eligible organization types include public and private institutions of higher education, qualifying nonprofits, small businesses and other for-profit organizations, state and local governments, Tribal governments and organizations, independent school districts, public and Indian housing authorities, faith-based and community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions, subject to the full NIH eligibility rules.
Submission: Applications are submitted electronically through Grants.gov using NIH ASSIST, an institutional system-to-system solution, or Grants.gov Workspace, and are tracked in eRA Commons. Required registrations must be active by the deadline.
Research controls: The NOFO is clinical-trial optional. Human-subjects projects are expected to use applicable NIMH Common Data Elements, and funded investigators are expected to share scientific data through the NIMH Data Archive under the NOFO’s data-management requirements.
Prospective applicants should review the complete NOFO for responsiveness, research-stage expectations, human-subjects and clinical-trial requirements, data-sharing obligations, and all current NIH submission instructions before applying.
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Source verificationOfficial government source · files.simpler.grants.govAtlas last verified this record October 3, 2026. Always use the funder's current application materials, amendments and portal instructions as the controlling source.View source and application materials ↗
