Opportunity Overview
The Mississippi Opioid Settlement Fund Advisory Council is accepting 2026 applications for projects that treat, prevent, surveil or reduce opioid use disorder or opioid misuse, or otherwise remediate harms from the opioid epidemic. Grant proceeds must benefit Mississippi residents. The Council recommends projects and funding amounts; final funding remains subject to Mississippi legislative appropriation and execution of a grant agreement.
Current Deadline — Extension Controls
The formal August 24 solicitation PDF still shows the original October 5 deadline, but the official live application page expressly states that dates on that page are authoritative and extends the deadline to October 12, 2026 at 5:00 PM Central Time. Atlas therefore uses the October 12 extension as the controlling current deadline.
Who Can Apply
Current official guidance lists 501(c)(3) nonprofits, counties and municipalities, faith-based organizations, health systems and healthcare providers, educational institutions, Mississippi-incorporated for-profit organizations, and national organizations proposing a Mississippi-specific project. Applicants must satisfy applicable Mississippi incorporation/recognition and licensure or certification requirements and demonstrate that grant funds will benefit Mississippi residents.
Funding and Payment Structure
The Council has set no minimum or maximum award amount for the 2026 cycle. Applicants should request the amount their project actually requires and support every line with a clear basis and justification. Matching funds are not required, although cash or in-kind match is a scored sustainability consideration. Administrative costs may not exceed 10% of the award. Most awards are reimbursement-based; lump-sum payment is available only for projects of no more than $50,000. The anticipated performance period is July 1, 2027 through June 30, 2028, subject to appropriation.
Project and Budget Controls
Projects should align with one or more of Mississippi’s opioid strategy pillars and the Council’s published priorities, including prevention and early intervention, treatment and recovery access, community-based solutions, overdose and harm reduction, workforce and integration, and data-driven policy. Every non-administrative budget line must map to an approved opioid-remediation use under Exhibit E of the national opioid settlements. The application is completed online and requires organizational and financial documentation, project staffing qualifications, at least one and no more than three letters of support, and MOUs where applicable.
Atlas Analysis
This is a substantial statewide behavioral-health and opioid-abatement funding opportunity with unusually broad applicant eligibility and no stated award ceiling. Strong applications will be tightly tied to Mississippi-specific opioid harms, evidence-based treatment or prevention, measurable service delivery, county-level need, sustainable staffing and implementation, and a reimbursement-ready budget. Healthcare technology or telehealth should be included only where it is a necessary, evidence-supported component of an opioid-abatement service model; the solicitation does not itself create a general-purpose telehealth or device-purchase pathway.
Source verification: Mississippi Attorney General’s Office / Mississippi Opioid Settlement Fund Advisory Council 2026 grant portal and formal solicitation. Atlas last verified September 25, 2026. The live portal is the controlling source for the deadline extension.