Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R01 – Clinical Trial Optional)

Official funding announcement — preliminary draft

Funder: National Institutes of Health

Opportunity number: PAR-25-265

Official listed status: posted

Closing information: 2027-11-16 (official deadline clock time and time zone must be checked in NOFO)

Award disclosure: Applicant-level ceiling not stated in the retrieved federal synopsis; verify in full NOFO.

Applicant categories in federal synopsis: City or township governments; Public and State controlled institutions of higher education; Private institutions of higher education; Special district governments; Native American tribal governments (Federally recognized); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Public housing authorities/Indian housing authorities; Small businesses; For profit organizations other than small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); State governments; Native American tribal organizations (other than Federally recognized tribal governments); Independent school districts; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; County governments

Federal synopsis

This FOA encourages research relevant to the development of novel screening approaches and/or therapeutic interventions for potentially fatal or disabling conditions that have been identified through newborn screening, as well as for "high priority" genetic conditions where screening may be possible in the near future.Having an accurate screening test, as well as demonstrating the benefits of early intervention or treatment, are important criteria for including a condition on a newborn screening panel. This FOA defines a "high priority" condition as one where screening is not currently recommended, but infants with the condition would significantly benefit from early identification and treatment.

Draft intake record. Eligibility, program terms, current amendments and applicant ceiling must be independently verified before publishing.

Official Grants.gov opportunity and NOFO