Official funding announcement — preliminary draft
Funder: National Institutes of Health
Opportunity number: PAR-25-182
Official listed status: posted
Closing information: 2027-10-15 (official deadline clock time and time zone must be checked in NOFO)
Award disclosure: Applicant-level ceiling not stated in the retrieved federal synopsis; verify in full NOFO.
Applicant categories in federal synopsis: Native American tribal organizations (other than Federally recognized tribal governments); Special district governments; State governments; Small businesses; Public and State controlled institutions of higher education; Public housing authorities/Indian housing authorities; Independent school districts; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; Native American tribal governments (Federally recognized); Private institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); City or township governments; County governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Federal synopsis
Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R61/R33 Clinical Trial Required). As part of NIMH's clinical trials pipeline, this NOFO encourages pilot research developing and testing novel psychosocial interventions and/or targets. Consistent with NIMH's emphasis on the experimental therapeutics approach to intervention development, it intends to speed the translation of emergent research in basic, behavioral, cognitive, affect, and neuropsychological science into preventative or therapeutic interventions. This RFA will provide up to two years of support for evaluation of target engagement and establishment of intervention parameters, and up to three years of support to replicate target engagement from prior studies and to test the association between target engagement and change in clinical outcome(s).
Draft intake record. Eligibility, program terms, current amendments and applicant ceiling must be independently verified before publishing.