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GrantNIH BRAIN Initiative Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UG3/UH3 Clinical Trial Optional) — RFA-NS-25-021
Atlas Opportunity Score96/100
FundingNIH anticipates approximately $10 million per year for 5-7 awards. UG3 direct costs may not exceed $500,000/year; UH3 direct costs should rarely exceed $1,500,000/year. UG3 maximum 1 year, UH3 maximum 4 years, total maximum 5 years. No cost sharing required.
DeadlineSeptember 28, 2026 at 5:00 PM local time of the applicant organization.
Required next actionRoute to established CNS neurotechnology/device teams with qualifying recording or stimulation technology, IP/manufacturer relationships, FDA/IDE capability, engineering and clinical expertise, quantitative milestones, and appropriate human-subject research infrastructure. Proceed only when those mandatory capabilities are independently verified.
Current statusActive — applications due September 28, 2026 at 5:00 PM local time of the applicant organization; NOFO expires September 29, 2026.Source verificationSeptember 28, 2026
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How Atlas Scores Fit
Useful enough to guide action, structured enough to scale.
Strategic Alignment
How directly the organization's goals and use case match the funder's priorities.
Funding Potential
Available dollars, allowable uses, match burden and the amount that can realistically support the project.
Actionability
Deadline, documentation burden, readiness and the practical work required to submit a strong application.
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