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GrantNIH INCLUDE Clinical Trials Phased Awards for Down syndrome Research (R61/R33, Clinical Trial Required) – RFA-OD-27-005
Atlas Opportunity Score91/100
FundingNIH intends to commit an estimated $3,000,000 to fund up to 4 awards per year in FY2027, FY2028, and FY2029. R61 and R33 budgets are not formally capped but must reflect actual project needs. Maximum combined project period 5 years: up to 2 years R61 plus up to 3 years R33. Cost sharing is not required.
DeadlineOctober 15, 2026 at 5:00 PM local time of the applicant organization. Open date: September 15, 2026.
Required next actionBefore submission, validate a responsive Down syndrome clinical-trial concept, qualified PD/PI and study team, recruitment and site capacity, human-subjects and IRB readiness, DSMB planning, milestone criteria for R61-to-R33 transition, data-sharing requirements, and active SAM, UEI, Grants.gov, and eRA Commons registrations.
Current statusActiveSource verificationOctober 3, 2026
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