OPEN: 2027 SVRF Career Development Track LOI accepting submissions through November 10, 2026, 5:00 p.m. PST. Invitation-only full proposals due February 2, 2027, 5:00 p.m. PST. Controlling 2027 RFA verified November 1, 2026.
National – Additional Ventures 2027 Single Ventricle Research Fund: Career Development Track (Up to $300,000; November 10 LOI)
FundingUp to $300,000 in direct costs per 2027 SVRF Career Development Track award over three years, plus up to 10% indirect costs under funder policy. Overall 2027 funding pool not published.
Deadline2027 SVRF Career Development Track letter of intent due November 10, 2026 at 5:00 p.m. Pacific Standard Time (PST); invited full proposal due February 2, 2027 at 5:00 p.m. PST. Invitations announced by December 15, 2026.
Last verified2026-11-01
Required next actionReview the 11-page Additional Ventures 2027 RFA. Verify PI holds doctorate, mentored non-independent appointment, generally within ten years of terminal degree (exceptions in RFA); eligible host nonprofit academic/research or qualifying governmental biomedical research institution, U.S. or international legal restrictions. Use ProposalCentral to submit 2027 Career Development Track LOI by November 10, 2026 at 5:00 p.m. PST. LOI includes 500-character project summary, 2500-character strategy, 500-character impact statement and institutional officials. One LOI per investigator; no multiple lead-investigator collaboration. If invited, submit full proposal February 2, 2027 at 5:00 p.m. PST, including mentor roles, biosketches, detailed budget, research plan and applicable ethics approvals.
Broad Eligibility
Mentored non-independent postdoctoral or equivalent doctoral-level investigator, normally within ten years of terminal degree with specified exceptions for leave/caregiving etc. Applicant host is nonprofit academic/research institution, university, medical school or certain governmental biomedical research organizations worldwide, subject to U.S. sanctions and legal restrictions. One to five independent mentors/advisors can be listed as co-investigators, but no multi-lead collaborative proposal in this track. Mechanistic foundational research relevant to single ventricle disease long-term sequelae, not clinical trials, stand-alone registries/biorepositories or primarily prototype development.
Atlas Analysis
Source verified November 1, 2026 against Additional Ventures controlling 11-page 2027 RFA at https://research-authority.tau.ac.il/sites/resauth.tau.ac.il/files/Additional-Ventures-2027-SVRF-RFP.pdf and official current program https://www.additionalventures.org/funding/single-ventricle-research-fund/. RFA page 3: Career Development individual awards up to $300,000 direct costs over three years, up to 10% indirect additional; overall pool not stated. LOI Nov 10, 2026 5pm PST; invited full proposals Feb 2, 2027 5pm PST; invitations Dec 15. RFA page 5: PI doctoral degree, mentored appointment within 10 years doctorate with exceptions, qualified nonprofit institutional host domestic or internationally subject to sanctions; advisors/mentors as co-investigators minimum 1 maximum 5. ProposalCentral required. Expenses include researcher salary subject NIH cap, reagents, equipment, tuition, software, fringe, travel and dissemination. No required cash match published. IRB/IACUC before initial payment where applicable; institutional award not to individual. Genuine competitive financial assistance; distinct from Independent Investigator Track. No inventing the overall funding pool.
Additional Ventures 2027 Single Ventricle Research Fund: Career Development Track
Additional Ventures is accepting the 2027 Single Ventricle Research Fund letter-of-intent stage for mentored, early-career researchers working on foundational mechanisms of single ventricle heart disease. This is an applicant research award, not a consulting or vendor procurement notice.
Applicant funding and deadlines
Up to $300,000 in direct costs over three years is available for an individual Career Development Track grant. Indirect costs of up to 10 percent are provided in addition. The public 2027 program page does not specify a universal matching-funds obligation or overall program funding pool.
Letter of intent deadline: November 10, 2026, 5:00 p.m. Pacific Standard Time (PST). The controlling 2027 Request for Proposals confirms the closing hour. Full proposals are invitation-only, due February 2, 2027, 5:00 p.m. PST, following invitation decisions by December 15, 2026. Anticipated award funding begins July 1, 2027.
Eligibility and research fit
Eligible lead applicants are doctoral-level postdoctoral fellows or equivalent researchers in mentored, non-independent positions, normally within ten years of the terminal doctorate, with published exceptions for qualifying leave and other circumstances. The Career Development Track does not accept collaborative projects with multiple lead investigators, but the 2027 RFA permits one to five independent mentors or advisors as co-investigators. Applicants must be affiliated with qualifying nonprofit academic or research organizations, eligible universities or certain biomedical governmental research agencies in the United States or abroad. U.S. legal and sanctions restrictions apply.
Supported projects examine foundational biological, physiological or related mechanisms underlying complications and long-term outcomes of single ventricle heart disease. Priorities include multi-organ dysfunction, circulatory physiology, cardiac rhythm, liver and kidney perfusion, lymphatic and immune issues, and neurodevelopment. Clinical trials, stand-alone registries or biorepositories, and projects primarily pursuing device design or precommercial optimization do not qualify.
How to apply
Apply through ProposalCentral (www.proposalcentral.com) by selecting the Single Ventricle Research Fund and the Career Development Track, and submit the LOI by November 10, 2026 at 5:00 p.m. PST. Only one LOI may be submitted by each investigator. Applicants provide institution and PI details, project summary (500 characters), goals and methods (2,500 characters), and impact statement (500 characters). Full proposals require an invitation; invited applicants must submit institutional/mentor details, research plan, budget, biosketches and other materials by February 2, 2027 at 5:00 p.m. PST. Awards go to the eligible host institution, not individuals. Official 2027 program: https://www.additionalventures.org/funding/single-ventricle-research-fund/ . Controlling 2027 RFA: https://research-authority.tau.ac.il/sites/resauth.tau.ac.il/files/Additional-Ventures-2027-SVRF-RFP.pdf .
Source verificationReferenced source · www.additionalventures.orgAtlas last verified this record 2026-11-01. Always use the funder's current application materials, amendments and portal instructions as the controlling source.View source and application materials ↗
