Official funding announcement — preliminary draft
Funder: National Institutes of Health
Opportunity number: PAR-28-091
Official listed status: posted
Closing information: 2029-11-16 (official deadline clock time and time zone must be checked in NOFO)
Award disclosure: Official federal synopsis lists an award ceiling of 500,000; applicant-level applicability requires full-NOFO review.
Applicant categories in federal synopsis: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; City or township governments; Native American tribal organizations (other than Federally recognized tribal governments); Native American tribal governments (Federally recognized); Others (see text field entitled "Additional Information on Eligibility" for clarification); Special district governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; County governments; Public housing authorities/Indian housing authorities; State governments; For profit organizations other than small businesses; Private institutions of higher education; Independent school districts; Public and State controlled institutions of higher education
Federal synopsis
The National Center for Complementary and Integrative Health (NCCIH) announces this Notice of Funding Opportunity (NOFO) to solicit applications for multi-site feasibility trials of complementary and integrative health approaches with physical and/or psychological therapeutic inputs (often called mind and body interventions) to reproduce and translate mechanisms of emotional well-being (EWB) into large-scale clinical trials that advance our understanding of whole person health. These early-phase multi-site trials are essential for 1) demonstrating that the mind and body intervention can be delivered with fidelity across sites; 2) demonstrating reproducibility and rigor in engaging targeted mechanisms of EWB by the mind and body intervention across sites; 3) assessing feasibility of participant recruitment and retention, as well as randomization; 4) assessing feasibility of collecting comprehensive clinical (whole person health restoration) and mechanistic (EWB) data across sites; and 5) exploring correlations between changes in mechanistic targets and clinical outcome measurements pooled across sites. By laying this groundwork, studies supported under this NOFO will advance the science of whole person health and prepare the field for rigorous clinical trials and mechanistic mediation analysis with the potential to improve the health and well-being of all Americans.
Draft intake record. Eligibility, program terms, current amendments and applicant ceiling must be independently verified before publishing.