Official funding announcement — preliminary draft
Funder: National Institutes of Health
Opportunity number: PAR-25-026
Official listed status: posted
Closing information: 2027-01-07 (official deadline clock time and time zone must be checked in NOFO)
Award disclosure: Applicant-level ceiling not stated in the retrieved federal synopsis; verify in full NOFO.
Applicant categories in federal synopsis: Public housing authorities/Indian housing authorities; State governments; Private institutions of higher education; For profit organizations other than small businesses; Public and State controlled institutions of higher education; Independent school districts; Native American tribal organizations (other than Federally recognized tribal governments); Others (see text field entitled "Additional Information on Eligibility" for clarification); City or township governments; County governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Special district governments; Native American tribal governments (Federally recognized); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Federal synopsis
The objective of this funding opportunity is to support investigator-initiated, Phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders in adults and children. In addition to supporting clinical trial start-up and implementation activities, this FOA will provide support for final stage preclinical activities needed for the implementation of the proposed trial. All the activities proposed in the R61 phase must be directly related to the therapeutic/diagnostic in preparation for the clinical trial. The proposed trial can be single or multisite. This NOFO will utilize a bi-phasic, milestone-driven mechanism of award where the first phase can be used to finalize required pre-trial activities such as stability, shipping studies, and site training.
Draft intake record. Eligibility, program terms, current amendments and applicant ceiling must be independently verified before publishing.