Official funding announcement — preliminary draft
Funder: National Institutes of Health
Opportunity number: PAR-25-207
Official listed status: posted
Closing information: 2028-01-07 (official deadline clock time and time zone must be checked in NOFO)
Award disclosure: Applicant-level ceiling not stated in the retrieved federal synopsis; verify in full NOFO.
Applicant categories in federal synopsis: Others (see text field entitled "Additional Information on Eligibility" for clarification); For profit organizations other than small businesses; Public and State controlled institutions of higher education; City or township governments; Small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Independent school districts; Native American tribal organizations (other than Federally recognized tribal governments); Public housing authorities/Indian housing authorities; Special district governments; Native American tribal governments (Federally recognized); County governments; State governments
Federal synopsis
NIMH seeks applications for research projects to evaluate the effectiveness of therapeutic and service delivery interventions for the post-acute management of mental health conditions affecting youth, adults, and older adults. This Notice of Funding Opportunity (NOFO) encourages clinical trials to establish the effectiveness and test hypotheses regarding moderators, mediators, and mechanisms of action of post-acute phase therapeutic and services interventions that are matched to the stage of illness in terms of both their focus (e.g., consolidating and maintaining gains from initial treatment, managing residual symptoms/impairment, preventing relapse, promoting adherence and appropriate service use) and intensity/burden for promoting optimal longer-term outcomes. This NOFO is intended to support effectiveness trials testing post-acute phase interventions that are statistically powered to provide a definitive answer regarding the study intervention's effectiveness. Support for pilot effectiveness trials to evaluate the initial feasibility, tolerability, acceptability, safety and preliminary indications of effectiveness of post-acute phase intervention approaches is provided via a companion R34 (Currently TEMP-24814)
Draft intake record. Eligibility, program terms, current amendments and applicant ceiling must be independently verified before publishing.