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PAR-25-101

Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional)

Official Grants.gov opportunity PAR-25-101 from National Institutes of Health. Requires full eligibility, amount, controlling deadline, award-type and duplication QA before publication.

FundingOfficial federal synopsis lists an award ceiling of 150,000; applicant-level applicability requires full-NOFO review.
Deadline2027-08-11 (official deadline clock time and time zone must be checked in NOFO)
Last verifiedAtlas review
Required next actionReview the official full announcement, amendments and submission portal requirements before applying.

Broad Eligibility

Native American tribal organizations (other than Federally recognized tribal governments); For profit organizations other than small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public housing authorities/Indian housing authorities; County governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; Special district governments; State governments; City or township governments; Independent school districts; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Small businesses; Native American tribal governments (Federally recognized)

Official funding announcement — preliminary draft

Funder: National Institutes of Health

Opportunity number: PAR-25-101

Official listed status: posted

Closing information: 2027-08-11 (official deadline clock time and time zone must be checked in NOFO)

Award disclosure: Official federal synopsis lists an award ceiling of 150,000; applicant-level applicability requires full-NOFO review.

Applicant categories in federal synopsis: Native American tribal organizations (other than Federally recognized tribal governments); For profit organizations other than small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public housing authorities/Indian housing authorities; County governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; Special district governments; State governments; City or township governments; Independent school districts; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Small businesses; Native American tribal governments (Federally recognized)

Federal synopsis

The National Institute on Drug Abuse (NIDA) Cutting-Edge Basic Research Award (CEBRA) is designed to foster highly innovative or conceptually creative research related to the etiology, pathophysiology, prevention, or treatment of substance use disorders (SUDs). It supports high-risk and potentially high-impact research that is sparse or not included in NIDA's current portfolio that has the potential to transform SUD research. The proposed research should: 1. develop, and/or adapt, revolutionary techniques or methods for addiction research or that show promising future applicability to SUD research; and /or 2. test an innovative and significant hypothesis for which there are scant precedent or preliminary data and which, if confirmed, would transform current thinking.

Draft intake record. Eligibility, program terms, current amendments and applicant ceiling must be independently verified before publishing.

Official Grants.gov opportunity and NOFO

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Source verificationOfficial government source · www.grants.govAtlas last verified this record during its latest review. Always use the funder's current application materials, amendments and portal instructions as the controlling source.View source and application materials ↗