The National Institutes of Health is accepting R03 applications under PAR-25-233, Dissemination and Implementation Research in Health. The program supports small studies that advance the science of dissemination and implementation of evidence-based health interventions, including adoption, adaptation, integration, sustainability, scale-up, spread, de-implementation, and D&I methods and measures.
Next new-application deadline: October 16, 2026 at 5:00 PM local time of the applicant organization. The next resubmission deadline is November 16, 2026 at 5:00 PM applicant-local time.
Funding: Applicants may request up to $50,000 per year in direct costs for up to two years. Cost sharing is not required. The number of awards depends on NIH appropriations and submission of sufficiently meritorious applications.
Eligibility: Eligible organization types include public and private institutions of higher education, nonprofit organizations, small businesses and other for-profit organizations, state and local governments, independent school districts, tribal entities, faith- and community-based organizations, regional organizations, and certain foreign organizations. Qualified individuals with the appropriate skills, knowledge, resources, and institutional support may serve as PD/PI, subject to NIH registration requirements.
Program requirements and restrictions: Proposed work must fit the mission and interests of a participating NIH Institute or Center and be appropriately sized for the R03 mechanism. The NOFO supports rigorous D&I research using relevant frameworks, contextual analysis, implementation outcomes, stakeholder engagement, and appropriate study designs. Clinical trials are not allowed. Applications that propose to test therapies, imaging, diagnostics, biologics, or devices, or that propose an intervention efficacy trial, are non-responsive.
Submission: Applications are submitted through NIH ASSIST, Grants.gov Workspace, or an institutional system-to-system solution in accordance with the NIH application guide.
Atlas fit: Strong Arkansas relevance for implementation-science teams working in rural health, behavioral health, aging, maternal/pediatric care, community health, cancer control, or other participating NIH mission areas. N9+ fit is moderate and conditional: it may be scientifically relevant where the D&I question concerns implementation, scale-up, sustainment, or de-implementation of a telehealth or guided remote-examination workflow and remote examination/vitals data are genuinely material. N9+ should not be positioned as a stand-alone equipment purchase or as the intervention being tested for efficacy. A partner-led research collaboration or technology-support role is the preferred Dr. Miltie pathway.